The process of achieving a strategic balance of intervention effectiveness, affordability, scalability, and efficiency.
MOST is a principled approach to developing interventions that achieve a strategic balance called EASE.
We are a collective of data scientists passionate about helping researchers develop interventions that are effective and efficient.
CADIO at NYU is advancing the MOST framework as the conceptual foundation for conducting intervention optimization research.
The d3center is developing and sharing methods and tools for optimizing adaptive interventions in the context of MOST.
The Reinforcement Learning Lab at Harvard is developing RL algorithms to inform next-gen, AI-powered adaptive interventions.
The researchers aim to develop innovative approaches that enhance drug bioavailability, reduce side effects, and optimize treatment regimens for various diseases.
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Adaptive interventions are intervention delivery frameworks that guide how dynamic information should be used in practice to modify an intervention.
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ORTCs are designed to systematically assess the performance of intervention components.
Learn MoreDuring the preparation phase, researchers lay the groundwork for optimization.
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MRTs are a powerful tool for optimizing interventions that adapt treatment on a relatively fast timescale.
Learn MoreIn a factorial ORCT, each candidate component is represented by an independent variable called a factor.
Learn MoreFor a limited time, we are offering MOST Training Workshops that are specifically geared towards those who identify as early career professionals. Our 2024 Workshops will be offered at a reduced rate. Priority will be given to early career professionals, but all are invited to apply.
"I went into this knowing very little about MOST and optimization trials. The content gave me more confidence using these methods in my work."
- January 2023 Training Participant
Resources on intervention optimization—the Multiphase Optimization Strategy [MOST], factorial designs, and more—including training opportunities, recommended reading, concept summaries, and more .
Visit CADIO
Resources specific to the optimization of adaptive interventions, including project summaries, online courses, experimental design and intervention framework overviews, and open-source code.
Visit d3center
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